Bioactive traditional plant <i>Cinnamomum zeylanicum</i> successfully combat against nephrotoxic effects of aminoglycosides
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چکیده
منابع مشابه
Protective role of Triphala, an Indian traditional herbal formulation, against the nephrotoxic effects of bromobenzene in Wistar albino rats.
OBJECTIVE The purpose of the present study was to evaluate the nephroprotective and antioxidant properties of Triphala against bromobenzene-induced nephrotoxicity in female Wistar albino rats. METHODS Animals were divided into five groups of six rats and treated as follows: Group I was a normal control and received no treatment, Group II received only bromobenzene (10 mmol/kg), Groups III and...
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Cadmium is a modern toxic metal and is a by-product of zinc and lead mining and smelting, which are important sources of environmental pollution. In humans, the kidney is recognized as the most critical organ affected by chronic exposure to cadmium. The present study was designed to explore the renotoxic effects of intraperitoneal acute administration of CdCl2 (0.32 mg/kg b.w.) in albino mice. ...
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Aminoglycosides are the commonly used antibiotics against Gram negative bacteria. Their clinical applications are limited due to nephrotoxic side effects. Therefore, the current study was undertaken in an attempt to increase the use of these drugs without causing nephrotoxicity by exploring the nephroprotective effects of a medicinal plant with high flavonoid contents and strong antioxidant pro...
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In vitro assays are economical and easy to perform but to establish relevance of their results to real clinical outcome in animals or human, pharmacokinetics is prerequisite. Despite various in vitro pharmacological activities of extracts of Piper sarmentosum, there is no report of pharmacokinetics. Therefore, the present study aimed to evaluate ethanol extract of fruit of the plant in dose of ...
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Recent studies have demonstrated that flavonoid glucuronides can be deconjugated to the active form aglycone by β-glucuronidase-expressing macrophages. Keigairengyoto (KRT) is a flavonoid-rich traditional Japanese medicine reported to enhance bacterial clearance through immune modulation. Our aims are to examine the pharmacokinetics of KRT flavonoids and to identify active flavonoids contributi...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2013
ISSN: 1991-0088,1991-007X
DOI: 10.3329/bjp.v8i1.12862